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Date: Mon, 14 Jul 1997 17:04:06 -0700
To: (Recipient list suppressed)
From: Paul Andrew Mitchell [address in tool bar]
Subject: SLS: CRITICAL INFORMATION ON TREATMENTS FOR ANTHRAX - JUST IN
  CASE! (fwd)

caveat emptor

/s/ Paul Mitchell
http://www.supremelaw.com


<snip>
>
>IF THE GERM WARFARE SCARE IS REAL, 
>THIS INFORMATION WILL BE VITAL!
>
>MOST DOCTORS HAVE 
>NEVER SEEN ANTHRAX BEFORE!
>
>From: Terry W. Stough,  <A
HREF="http://members.aol.com/TWStough/main.htm">The
> American Resistance Movement</A> 
>
>INFORMATION OBTAINED FROM 
>USUALLY RELIABLE SOURCES -- 
>NO GUARANTEE OF ACCURACY
>
>Colloidal silver will do nothing more than prolong your suffering a few more
>hours.  Check the CDC web site for info on antibiotics that are effective.
> Doxycillin is the cheapest of choice.   I include a report from MOM.
>
>TO: All Hands  ---  A Preliminary Report from Medical Corps 
>
>In medical language, a prophylaxis is a preventative; or a prevention against
>a disease.   As reported in an earlier article by Medical Corps we stated
>that there was no known prophylaxis against Anthrax. We now know of one. In
>point of fact, experimental treatment data indicates that daily doses of
>simple antibiotics -- even taken 24 hours AFTER exposure -- will shield a
>human from contracting Anthrax. Not only do the antibiotics protect against
>Anthrax, but existing studies strongly suggest that the same prophylaxis will
>work against Cholera and Plague.
>
>Not long after the first Anthrax article was printed, Medical Corps received
>a call from a lady who said that the U.S. Army had done studies using
> antibiotics as a prophylaxis against Antrax. The Corps agreed that this
>might work, but without verification, could not print it.  About a month
>later a copy of a report from the Journal of Infectious Diseases arrived.
>Unfortunately, two pages were missing-- still not verified. 
>
>Next stop was a VA Medical Research Center where this writer sifted through
>several volumes of the 50 or so Infectious Disease Journals in the VA Medical
>Library.  We now have that document intact.
> 
>The report is called: Postexposure Prophylaxis against Experimental
>Inhalation Anthrax (Journal of Infect. Dis. 1993; 167:1239-42) 
>
>The experiment was conducted by Dr. Arthur M. Friedlander, US Army Medical
>Research Institute of Infectious Diseases, Bacteriology Division, Fort
>Detrick, Frederick, MD 
>
>Rhesus monkeys (6 groups of 10 each, total: 60) were exposed to a heads-only
>challenge of air delivered Anthrax spores. Beginning one day after exposure,
>each of the six groups being tested were given the below treatment, with
>results as follows: 
>
>Treatment                                          Anthrax Deaths
>
>Control (untreated)                            9 out of 10 died
>
>Vaccine Alone                                   8 out of 10 died
>
>Penicillin                                            3 out of 10 died
>
>Ciprofloxacin                                     1 out of 10 died
>
>Doxycycline                                       1 out of 10 died
>
>Doxycycline + Vaccine                       0 out of 10 died
>
>Several things about this study are readily apparent.
>
>The antibiotics worked surprisingly well even when treatment was started a
>day after exposure.
>
>Given a day after exposure, the vaccine was a dismal failure.
>
>Without the prophylaxis, the chances of contracting the disease after being
>exposed to Inhalation Anthrax is almost a certainty. 
>
>The study was done on monkeys. While the Rhesus monkey responds to diseases
>and medications quite like a human, they are still animals. Human dosages
>will be different and the outcome may be better or not as successful.
>
>Before we discuss human dosages, consider these options: 
>
>a. If you contract Pulmonary Anthrax and you do not treat it, YOU WILL SURELY
>DIE! 
>
>b. Even with the most heroic treatment measures available in a hospital
>setting, your chances of surviving Pulmonary Anthrax are extremely remote.
>
>c. Human doses are determined by conversion calculations between animals and
>humans.  This is accomplished through blood level comparisons of MICs
>(Minimum Inhibitory Concentrations), dosage weight tables, peak and trough
>levels as well as various case studies.
>
>d. Additionally, human dosages were discussed with Pharmacists, Physicians,
>Clinicians and a former Chief of Medical Research of Oklahoma.
>
>What all of the above means is that the dosages will work and are as accurate
>as possible without human studies. 
>
>
>DOXYCYCLINE:
>
>Adult Dosages: Doxycycline  (Vibramycin) pills or capsules. **Prophylaxis
>Only** 
>
>Note: Adult weight is anyone weighing over 100 pounds. (PDR) 
>
>1) Minimum adult dosage for Doxycycline - 200 mg every twelve hours
>(BID/q12h) x 45 days.
>
>2) Maximum adult dosage for Doxycycline - 150  mg to 200 mg every eight hours
>(TID/q8h) x 60 days.
>
>Note:  When our survival depends upon antibiotics we tend to think that if
>this much is supposed to work then two or three times as much will be even
>better. Antibiotics are alien to the human body and in prescribed dosages are
>only mildly poisonous. 
>
>Taken in extreme doses they will damage your body or quite likely kill you. 
>
>Children Dosages: Doxycycline (Vibramycin)**Prophylaxis Only** 
>
>Dosages for children vary according to body weight and the drug being used.
>The Physicians Desk Reference (the PDR is a drug data book) states that for
>children above 100 pounds, the adult dose of Doxycycline should be used. 
>
>
>For children below 100 pounds, a daily recommended dose equaling 1mg per 1
>pound of body weight should be divided into two equal doses and given 12
>hours apart. (PDR) 
>
>For instance, a 60 lb. child would receive 60mg in two 30mg doses. However,
>Doxycycline tablets or capsules only come in 50 and 100mg sizes. Considering
>the insidious nature of Anthrax, it woud probably be better to give the 60
>lb. child a 25mg (1/2 of a 50mg tablet) dose every 8 hours (TID) for a daily
>total of 75mg of Doxycycline.
> 
>Note: A dose rate of q8h (every 8 hours) keeps the blood level of Doxycycline
>more constant within an adult or childs system. 
>
>A 40, 30, or 70 etc. pound child will require SEPARATE Doxycycline dosage
>computations using the formula 1mg per pound body weight. Then you will have
>to divide the dose into at least two or three equal parts and space evenly
>over one 24 hour day. 
>
>
>WARNINGS:
>
>1) Doxycycline is of the Tetracycline class of antibiotics and as with all
>Tetracyclines will cause yellowing and possibly destruction of the teeth in
>unborn babies, infants and children to the age of 8 years (source -- PDR).
>This condition has also been observed into the young adult years (Source --
>empirical data).
>
>2) Tetracyclines kill the normal/essential bacteria responsible for a healthy
>body. Among other things, this can cause ulcers of the mouth and diarrhea.
>
>3) If an allergy to any of the Tetracyclines develops or exists, discontinue
>and switch to a Penicillin class antibiotics
>
>
>4) Never use Penicillin and Tetracycline together. They tend to cancel each
>other out.
>
>5) Sunburn -- All Tetracyclines will make human skin extremely susceptible to
>sunburn.  As with all medication warnings, they must be weighed against the
>nature of the disease.  Pulmonary Anthrax will kill you. Yellow teeth won’t,
>and diarrhea can be dealt with.
>
>WARNING-- READ CAREFULLY:
>
>Tetracycline or Achromycin V were not used in the Prophylaxis study done by
>the U.S. Army! Conclusions that Tetracycline can be used as a prophylaxis
>were drawn from PDR dosages and the fact that Tetracycline is used to treat
>Cutaneous Anthrax (on the skin) before it enters the bodys system. 
>
>The drug of choice is DOXYCYCLINE! However . .. if you do not have
>Doxycycline and have access to Tetracycline, they are of the same class of
>antibiotics. They just have different dosages.
>
>TETRACYCLINE:   Adult Dosages: Tetracycline or Achromycin V. **Prophylaxis
>Only**
>
>Note: Adult dosages of Tetracycline are given to anyone over eight (8) years
>of age.  
>
>1) Minimum adult dosage for the Tetracyclines - 500mg every six hours
>(QID/q6h) x 45 days
>
>2) Maximum adult dosage for the Tetracyclines - 500mg every four hours (q4h)
>x 60 to 90 days 
>
>Children Dosages: Tetracyclines or Achromycin V **Prophylaxis Only** 
>
>
>Dosages for children vary according to body weight and the drug being used.
>The Physicians Desk Reference (drug data book) states that for children 8
>years and older, the adult dose of Tetracycline should be used. 
>
>For children 8 years and younger, a daily dose of Tetracycline equaling 10 to
>20mg per 1 pound of body weight should be divided into four equal doses and
>given 6 hours apart for 45 to 60 days.
>
>Note: There is no existing data on a prophylaxis dose of Tetracycline for
>either children or adults. A daily dose of 15mg per pound body weight divided
>into four equal doses might be more in order.
>
>For instance, a 60 lb. child taking 15mg per pound would compute to 900mg in
>four equal doses. This would round to 1000mg and stay within the 10 to 20mg
>dose range.  
>
>Since Tetracycline capsules only come in 250mg and 500mg sizes, the 60 lb.
>child could receive a 250mg dose every 4 hours.
>
>A dose rate may be varied an hour or so either way so as to make the total
>daily dose fit within a 24 hour period.
> 
>Too, the total daily dose of Tetracycline may be rounded up 10% or so, as to
>accommodate a workable dosage. 
>
>Note: A 40, 30, or 70 etc. pound child will require SEPARATE Tetracycline
>dosage computations using the formula 10 to 20mg per pound body weight. Then
>you will have to divide the dose into at least four (4) equal parts and space
>evenly over one 24 hour day. 
>
>WARNINGS:
>
>1) Tetracycline class antibiotics will cause yellowing of the teeth in unborn
>babies, infants and children to the age of 8 years (source -- PDR).
>
>2) All Tetracyclines kill the normal/essential bacteria responsible for a
>healthy body.
>
>3) If an allergy to any of the Tetracyclines develops or exists, discontinue
>and switch to a Penicillin class antibiotic.
>
>4) Never use Penicillin and Tetracycline together.They tend to cancel each
>other out.
>
>5) Sunburn-- All Tetracyclines will make human skin extremely susceptible to
>sunlight.
>
>6) Tetracycline and milk should not be taken together or within one (1) hour
>of each other. Milk and Tetracycline combine in the stomach and pass out of
>the body without the  Tetracycline being used.
>
>Remember, Pulmonary Anthrax will kill you.
>
> 
>ANIMAL GRADE ANTIBIOTICS:
>
>Tetracycline Class -- Terramycin, Oxytetracycline, Tetracycline (Bolus or
>Powder)
>
>These drugs are not the same as those used in hospitals!!! While animal grade
>Tetracycline is the same as Human grade Tetracycline -- the animal has a
>different volume due to the filler. However, you do not need grinders and
>bullet scales to arrive at a safe oral dosage.
>
>Look at the package. If it says 200mg of Tetracycline per teaspoon, and you
>need to take 500mg, then 2 1/2 teaspoons computes to 500mg. If the bag says
>1000mg per tsp, then you take 1/2 tsp. for the same 500mg. 
>Read the bag! If you cannot figure out the dosage from the information on the
>bag, check a different brand. 
>
>If the dosage is in grams, remember that it takes 1000mg to make one gram.  
>
>If the instructions are in milligrams per gram of powder find another
>bag--unless you just like to weigh things.
> 
>DO NOT USE injectable animal antibiotics! They do not usually contain
>Lidocaine (a local pain killer), which means you will suffer greatly from
>just one shot. Add to that pain the increased volume of the animal shot and
>you might prefer death. THEY ARE NOT THE SAME AS HUMAN INJECTABLES! 
>
>======= THE FOLLOWING IS PART OF A C.D.C. REPORT ========
>                                                  
>
>[Emerging Infectious Diseases * Volume 3 * Number 2 * April-June 1997]
>
>Perspective
>
>The Economic Impact of a Bioterrorist Attack: Are Prevention and Postattack
>Intervention Programs Justifiable?
>
>Arnold F. Kaufmann, Martin I. Meltzer, and George P. Schmid 
>Centers for Disease Control and Prevention, Atlanta, Georgia, USA
>
>The epidemic curve for anthrax by days after exposure was assumed to be <1
>day, 0% of cases; 1 day, 5%; 2 days, 20%; 3 days, 35%; 4 days, 20%; 5 days,
>10%; 6 days, 5%; and 7 or more days, 5% (3-5). Case-fatality rates were also
>assumed to vary by the day symptoms were first noted. The case-fatality rate
>was estimated as 85% for patients with symptoms on day 1; 80% for patients
>with symptoms on day 2; 70% for those with symptoms on day 3; 50% for those
>with symptoms on days 4, 5, and 6; and 70% for those with symptoms on and
>after day 7. The increased death rate in persons with an incubation period of
>7 or more days is calculated on an assumption of delayed diagnosis, with
>resultant delayed therapy.
>
>When estimating days in hospital and outpatient visits due to infection, we
>assumed that 95% of anthrax patients were hospitalized, with a mean stay of 7
>days. Patients not admitted to a hospital had an average of seven outpatient
>visits, and surviving hospitalized patients had two outpatient
>visits after discharge from the hospital. Persons who received only
>outpatient care were treated for 28 days with either oral ciprofloxacin or
>doxycycline.
>
>
>
>
>
>

========================================================================
Paul Andrew Mitchell                 : Counselor at Law, federal witness
B.A., Political Science, UCLA;  M.S., Public Administration, U.C. Irvine

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